EYA3 Antikörper (AA 1-30)
Kurzübersicht für EYA3 Antikörper (AA 1-30) (ABIN7448559)
Target
Alle EYA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 1-30
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Verwendungszweck
 - Rabbit anti-EYA3 IHC Antibody, Affinity Purified
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Homologie
 - Mouse,Sheep,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Small-eared galago,Northern white-cheeked gibbon,Gray short-tailed opossum,White-tufted-ear marmoset,Crab-eating macaque
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Aufreinigung
 - Affinity Purified
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Immunogen
 - Between AA 1 and 30
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Isotyp
 - IgG
 
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Applikationshinweise
 - 1:100 - 1:500
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 250 μg/mL
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Buffer
 - Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
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Haltbarkeit
 - 12 months
 
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- EYA3 (Eyes Absent Homolog 3 (EYA3))
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Andere Bezeichnung
 - EYA3
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Hintergrund
 - Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].
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Gen-ID
 - 2140
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NCBI Accession
 - NP_001981
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UniProt
 - Q99504
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Pathways
 - Positive Regulation of Response to DNA Damage Stimulus
 
Target
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