CSN2 Antikörper (AA 1-50)

Produktnummer ABIN7448492

Der Kaninchen Polyklonal Anti-CSN2-Antikörper wurde für IHC validiert. Er ist geeignet, CSN2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CSN2 Antikörper (AA 1-50) (ABIN7448492)

Target: CSN2 (Casein beta (CSN2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSN2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-CSN2 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-CSN2 IHC Antibody, Affinity Purified

Homologie: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Nile tilapia,Crab-eating macaque,Tasmanian devil,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Gray short-tailed opossum,Zebra finch,Naked mole rat,Small-eared galago,Japanese pufferfish,African elephant,West Indian ocean coelacanth,Northern white-cheeked gibbon,Medaka fish,Three-spined stickleback,Spotted green pufferfish,Little brown bat

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CSN2

Target: CSN2 (Casein beta (CSN2))

Andere Bezeichnung: CSN2

Hintergrund: Background: CSN2 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals a function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN2 has also been demonstrated to interact with the sin3A corepressor complex as well as the thyroid hormone and vitamin D3 receptor to mediate gene repression.

Gen-ID: 9318

NCBI Accession: NP_004227

UniProt: P61201