PCNT Antikörper (AA 175-225)
Kurzübersicht für PCNT Antikörper (AA 175-225) (ABIN7448392)
Target
Alle PCNT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 175-225
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Verwendungszweck
- Rabbit anti-Pericentrin/Kendrin IHC Antibody, affinity purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 175 and 225
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PCNT (Pericentrin (PCNT))
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Andere Bezeichnung
- Pericentrin/Kendrin
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Hintergrund
- Background: Pericentrin (PCNT) is a large centrosomal protein that binds calmodulin and mediates assembly of the mitotic spindle apparatus. Depletion of PCNT has been shown to cause apoptosis and activation of the G2/M checkpoint. Recently, mutations in the pericentrin gene have been identified as the cause of primordial dwarfism type II (MOPDII) and Seckel syndrome. Additionally, in cells of Seckel syndrome patients, PCNT has been found to be important to the DNA damage response and ATR-dependent checkpoint signaling.
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Gen-ID
- 5116
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NCBI Accession
- NP_006022
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UniProt
- O95613
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Pathways
- Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interaktom
Target
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