MAP1LC3A Antikörper

Produktnummer ABIN7384463

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch MAP1LC3A in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MAP1LC3A Antikörper (ABIN7384463)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MAP1LC3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: R05-1B6

Produktdetails anti-MAP1LC3A Antikörper

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Andere Bezeichnung: LC3A

Hintergrund: ATG8E,Autophagy-related protein LC3 A,Autophagy-related ubiquitin-like modifier LC3 A,LC3,LC3A,MAP1 light chain 3 like protein 1,MAP1 light chain 3-like protein 1,MAP1A/1B light chain 3 A,MAP1A/MAP1B LC3 A,MAP1A/MAP1B light chain 3 A,MAP1ALC3,MAP1BLC3,Map1lc3a,Microtubule associated proteins 1A/1B light chain 3,Microtubule-associated protein 1 light chain 3 alpha,Microtubule-associated proteins 1A and 1B,light chain 3,Microtubule-associated proteins 1A/1B light chain 3A,MLP3A,LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.

Molekulargewicht:

Observed_MW: 16kDa

Calculated_MW: 14kDa

Gen-ID: 84557

UniProt: Q9H492

Pathways: Autophagie