ALIX Antikörper
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- Target Alle ALIX (PDCD6IP) Antikörper anzeigen
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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Reaktivität
- Human, Ratte, Hamster
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser ALIX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity Purified
- Klon
- R03-8C2
- Isotyp
- IgG
- Top Product
- Discover our top product PDCD6IP Primärantikörper
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- Applikationshinweise
- WB 1:1000-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
- Andere Bezeichnung
- ALIX (PDCD6IP Produkte)
- Hintergrund
- PDCD6IP,AIP1,ALIX,DRIP4,HP95,This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
- Molekulargewicht
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Observed_MW: 96kDa
Calculated_MW: 96kDa
- Gen-ID
- 10015
- UniProt
- Q8WUM4
- Pathways
- p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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