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ALIX Antikörper

PDCD6IP Reaktivität: Human, Ratte, Hamster WB Wirt: Kaninchen Monoclonal R03-8C2 unconjugated
Produktnummer ABIN7384341
  • Target Alle ALIX (PDCD6IP) Antikörper anzeigen
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Reaktivität
    • 75
    • 34
    • 31
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Hamster
    Wirt
    • 64
    • 13
    • 1
    Kaninchen
    Klonalität
    • 59
    • 18
    Monoklonal
    Konjugat
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser ALIX Antikörper ist unkonjugiert
    Applikation
    • 48
    • 26
    • 26
    • 21
    • 13
    • 13
    • 11
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity Purified
    Klon
    R03-8C2
    Isotyp
    IgG
    Top Product
    Discover our top product PDCD6IP Primärantikörper
  • Applikationshinweise
    WB 1:1000-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    300 μg/mL
    Buffer
    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Andere Bezeichnung
    ALIX (PDCD6IP Produkte)
    Hintergrund
    PDCD6IP,AIP1,ALIX,DRIP4,HP95,This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
    Molekulargewicht

    Observed_MW: 96kDa

    Calculated_MW: 96kDa

    Gen-ID
    10015
    UniProt
    Q8WUM4
    Pathways
    p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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