DOCK2 Antikörper

Produktnummer ABIN7384204

Produktdetails anti-DOCK2 Antikörper

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DOCK2 (NP_004937.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Andere Bezeichnung: DOCK2 (DOCK2 Produkte)

Synonyme: AI662014 antikoerper, AW122239 antikoerper, CED-5 antikoerper, Hch antikoerper, MBC antikoerper, dedicator of cytokinesis 2 antikoerper, dedicator of cyto-kinesis 2 antikoerper, DOCK2 antikoerper, dock2 antikoerper, Dock2 antikoerper

Hintergrund: DOCK2,IMD40,The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

Molekulargewicht:

Observed_MW: 240 kDa

Calculated_MW: 38 kDa/211 kDa

Gen-ID: 1794

UniProt: Q92608