Der Kaninchen Polyklonal anti-LRPPRC Antikörper wird verwendet zum Nachweis von LRPPRC in Proben von Human, Maus und Ratte. Er wurde validiert für IHC und IF.
LRPPRC,CLONE-23970,GP130,LRP130,LSFC,This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.