PFN2 Antikörper
Kurzübersicht für PFN2 Antikörper (ABIN7383994)
Target
Alle PFN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human PFN2
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PFN2 (Profilin 2 (PFN2))
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Andere Bezeichnung
- PFN2
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Hintergrund
- D3S1319E,PFL,PFN 2,Pfn2,PROF2,Profilin II,Profilin-2,Profilin2,ProfilinII,The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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Molekulargewicht
- 15 kDa
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NCBI Accession
- NP_444252
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UniProt
- P35080
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Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
Target
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