MERS-CoV Nucleocapsid Antikörper

Produktnummer ABIN7383848

Dieser Maus Monoklonal Antikörper erkennt spezifisch MERS-CoV Nucleocapsid in ELISA und WB. Er zeigt eine Reaktivität gegenüber Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

Kurzübersicht für MERS-CoV Nucleocapsid Antikörper (ABIN7383848)

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Reaktivität: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MERS-CoV Nucleocapsid Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: 1E1

Produktdetails anti-MERS-CoV Nucleocapsid Antikörper

Spezifität: Anti-MERS-CoV Nucleocapsid Monoclonal Antibody

Aufreinigung: Protein A Affinity

Immunogen: Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag), ABIN7198809

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MERS-CoV Nucleocapsid

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Andere Bezeichnung: MERS-CoV Nucleocapsid

Hintergrund: Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.