MERS-CoV Nucleocapsid Antikörper
Kurzübersicht für MERS-CoV Nucleocapsid Antikörper (ABIN7383849)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Anti-MERS-CoV Nucleocapsid Protein Polyclonal Antibody
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Aufreinigung
- Antigen Affinity
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Immunogen
- A synthetic peptide corresponding to the center region of MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein (NP protein)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-1:5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- 0.2 μm filtered solution in PBS
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))
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Andere Bezeichnung
- MERS-CoV Nucleocapsid Protein
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Hintergrund
- Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Target
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