CD73 Antikörper
Kurzübersicht für CD73 Antikörper (ABIN7271979)
Target
Alle CD73 (NT5E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
-
-
Verwendungszweck
- CD73 Unconjugated Antibody
-
Produktmerkmale
- The clone AD2, a mouse monoclonal antibody recognizes a 70kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase (or 5'-Ecto-nucleotidase) cell surface antigen known as CD73. It is widely expressed on various immune as well as non-immune cells including T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, epithelial cells, etc. CD73 catalyzes the conversion of extracellular nucleosides to adenosine and modulates immune responses. Administration of CD73 inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.
-
Aufreinigung
- Purified
-
Reinheit
- >95 %
-
Immunogen
- Pre-B leukemia cell line
-
Isotyp
- IgG1, kappa
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
-
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
-
Andere Bezeichnung
- CD73
-
Gen-ID
- 4907
-
UniProt
- P21589
-
Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
Target
-