IL7R Antikörper

Produktnummer ABIN7271839

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL7R in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL7R Antikörper (ABIN7271839)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL7R Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: 4G8

Produktdetails anti-IL7R Antikörper

Verwendungszweck: CD127 Unconjugated Antibody

Produktmerkmale: The clone 4G8, a mouse monoclonal antibody selectively recognizes a 60-90 kDa surface type 1 transmembrane glycoprotein antigen known as CD127 or IL-7 receptor α chain (IL-7Rα). CD127 forms a heterodimer with the common γ chain of the receptors of several cytokines such as IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. It is widely expressed on different subsets of B cells, peripheral T cells and bone marrow stromal cells. CD127 plays important role in the generation of memory and effector T cells as well as functional B cells.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Purified homodimeric form of T-ALL mutant and monomeric WT hIL-7Ralpha conjugated KLH

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: CD127

Gen-ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size