ZIC2 Antikörper (AA 1-220)

Produktnummer ABIN7271432

Der Kaninchen Polyklonal Anti-ZIC2-Antikörper wurde für WB validiert. Er ist geeignet, ZIC2 in Proben von Human zu detektieren.

Kurzübersicht für ZIC2 Antikörper (AA 1-220) (ABIN7271432)

Target: ZIC2

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZIC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZIC2 Antikörper

Bindungsspezifität: AA 1-220

Verwendungszweck: ZIC2 Rabbit pAb

Sequenz: MLLDAGPQFP AIGVGSFARH HHHSAAAAAA AAAEMQDREL SLAAAQNGFV DSAAAHMGAF KLNPGAHELS PGQSSAFTSQ GPGAYPGSAA AAAAAAALGP HAAHVGSYSG PPFNSTRDFL FRSRGFGDSA PGGGQHGLFG PGAGGLHHAH SDAQGHLLFP GLPEQHGPHG SQNVLNGQMR LGLPGEVFGR SEQYRQVASP RTDPYSAAQL HNQYGPMNMN

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ZIC2 (NP_009060.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZIC2

Target: ZIC2

Andere Bezeichnung: ZIC2

Hintergrund: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.,ZIC2,HPE5,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Neuroscience,ZIC2

Molekulargewicht: 55kDa

Gen-ID: 7546

UniProt: O95409

Pathways: Tube Formation