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ZIC2 Antikörper (AA 131-230)

ZIC2 Reaktivität: Ratte, Maus IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6989026
  • Target Alle ZIC2 Antikörper anzeigen
    ZIC2
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    Reaktivität
    • 18
    • 16
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 31
    • 2
    • 1
    Kaninchen
    Klonalität
    • 32
    • 2
    Polyklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ZIC2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Zic2
    Isotyp
    IgG
    Top Product
    Discover our top product ZIC2 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ZIC2
    Andere Bezeichnung
    Zic2 (ZIC2 Produkte)
    Synonyme
    HPE5 antikoerper, Ku antikoerper, cb851 antikoerper, fb26a03 antikoerper, wu:fb26a03 antikoerper, zic2 antikoerper, zic2.1 antikoerper, hpe5 antikoerper, hm:zeh0655 antikoerper, id:ibd5017 antikoerper, zic2.2 antikoerper, zic2l antikoerper, Zic family member 2 antikoerper, zinc finger protein of the cerebellum 2 antikoerper, zic family member 2 (odd-paired homolog, Drosophila), a antikoerper, Zic family member 2 L homeolog antikoerper, zic family member 2 (odd-paired homolog, Drosophila) b antikoerper, ZIC2 antikoerper, Zic2 antikoerper, zic2a antikoerper, zic2.L antikoerper, zic2b antikoerper
    Hintergrund

    Synonyms: HPE 5, HPE5, Odd paired homolog Drosophila, Zic 2, Zic family member 2 (odd paired Drosophila homolog), Zic family member 2, ZIC2, ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, Zinc finger protein Zic2.

    Background: Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.

    Gen-ID
    7546
    UniProt
    O95409
    Pathways
    Tube Formation
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