YBX1 Antikörper (AA 100-200)

Produktnummer ABIN7271411

Der Kaninchen Polyklonal Anti-YBX1-Antikörper wurde für WB und IF validiert. Er ist geeignet, YBX1 in Proben von Human zu detektieren.

Kurzübersicht für YBX1 Antikörper (AA 100-200) (ABIN7271411)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-YBX1 Antikörper

Bindungsspezifität: AA 100-200

Verwendungszweck: YB-1/YBX1 Rabbit pAb

Sequenz: LRSVGDGETV EFDVVEGEKG AEAANVTGPG GVPVQGSKYA ADRNHYRRYP RRRGPPRNYQ QNYQNSESGE KNEGSESAPE GQAQQRRPYR RRRFPPYYMR R

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YB-1/YB-1/YBX1 (NP_004550.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Andere Bezeichnung: YBX1

Hintergrund: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.,YBX1,BP-8,CBF-A,CSDA2,CSDB,DBPB,EFI-A,MDR-NF1,NSEP-1,NSEP1,YB-1,YB1,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,YBX1

Molekulargewicht: 35kDa

Gen-ID: 4904

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation