ULK3 Antikörper
Kurzübersicht für ULK3 Antikörper (ABIN7271222)
Target
Alle ULK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ULK3 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human ULK3
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Isotyp
- IgG
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibody
ULK3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibodyULK3 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (Internal Region) antibodyULK3 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 427-454), (C-Term) antibodyULK3 Reaktivität: Human, Maus, Ratte WB, IHC, ICC, FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 44-240) antibodyULK3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (Internal Region) antibodyULK3 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 347-375), (C-Term) antibodyULK3 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB33310 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 4C5 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 445-458) antibodyVerified ULK3 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (C-Term) antibodyVerified ULK3 Reaktivität: Human ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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Andere Bezeichnung
- ULK3
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Hintergrund
- Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3. Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.,Autophagy,Cell Biology & Developmental Biology,Endocrine & Metabolism,Kinase,Mitochondrial metabolism,Signal Transduction,ULK3
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Molekulargewicht
- 53kDa
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Gen-ID
- 25989
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UniProt
- Q6PHR2
Target
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