ULK3 Antikörper (Internal Region)
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- Target Alle ULK3 Antikörper anzeigen
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ULK3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- ULK3 Antibody detects endogenous levels of total ULK3.
- Homologie
- Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ULK3, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ULK3 Primärantikörper
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibody
ULK3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 390)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal Atto 390
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (HRP)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal HRP
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (FITC)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal FITC
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (PE)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal PE
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (PerCP)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal PerCP
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 594)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal Atto 594
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 488)ULK3 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal Atto 488
anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibodyULK3 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
- Andere Bezeichnung
- ULK3 (ULK3 Produkte)
- Synonyme
- zgc:162196 antikoerper, 1200015E14Rik antikoerper, unc-51 like kinase 3 antikoerper, unc-51 like kinase 3 L homeolog antikoerper, unc-51-like kinase 3 antikoerper, ULK3 antikoerper, ulk3 antikoerper, Ulk3 antikoerper, ulk3.L antikoerper
- Hintergrund
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Description: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Gene: ULK3
- Molekulargewicht
- 24 kDa
- Gen-ID
- 25989
- UniProt
- Q6PHR2
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