TARDBP Antikörper

Produktnummer ABIN7270730

Der Kaninchen-Monoklonal Anti-TARDBP-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet zum Nachweis von TARDBP in Proben aus Human. }

Kurzübersicht für TARDBP Antikörper (ABIN7270730)

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TARDBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TARDBP Antikörper

Verwendungszweck: TDP-43/TARDB Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TDP-43/TARDB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TARDBP

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Andere Bezeichnung: TARDBP

Hintergrund: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],ALS10,TDP-43,TARDBP,TDP43,Apoptosis,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyotrophic lateral sclerosis,ALS,Neuroscience,Other Neurological disorders,RNA Binding,TARDBP

Molekulargewicht: 45kDa

Gen-ID: 23435

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion