SNW1 Antikörper (AA 300-536)

Produktnummer ABIN7270386

Dieses Anti-SNW1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNW1 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für SNW1 Antikörper (AA 300-536) (ABIN7270386)

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNW1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SNW1 Antikörper

Bindungsspezifität: AA 300-536

Verwendungszweck: SNW1 Rabbit pAb

Sequenz: EAVEMRAQVE RKMAQKEKEK HEEKLREMAQ KARERRAGIK THVEKEDGEA RERDEIRHDR RKERQHDRNL SRAAPDKRSK LQRNENRDIS EVIALGVPNP RTSNEVQYDQ RLFNQSKGMD SGFAGGEDEI YNVYDQAWRG GKDMAQSIYR PSKNLDKDMY GDDLEARIKT NRFVPDKEFS GSDRRQRGRE GPVQFEEDPF GLDKFLEEAK QHGGSKRPSD SSRPKEHEHE GKKRRKE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-536 of human SNW1 (NP_036377.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Andere Bezeichnung: SNW1

Hintergrund: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.,SNW1,Bx42,NCOA-62,PRPF45,Prp45,SKIIP,SKIP,FUN20,SKIP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,SNW1

Molekulargewicht: 61kDa

Gen-ID: 22938

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway