SNW1 Antikörper (N-Term)

Produktnummer ABIN2779548

Der Kaninchen Polyklonal anti-SNW1 Antikörper (ABIN2779548) detektiert spezifisch SNW1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für SNW1 Antikörper (N-Term) (ABIN2779548)

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNW1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNW1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SKIIP Antibody - N-terminal region

Sequenz: RQGQSKDKVI YSKYTDLVPK EVMNADDPDL QRPDEEAIKE ITEKTRVALE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against SKIIP. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32294-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Andere Bezeichnung: SKIIP

Hintergrund:

Background Information: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Gene Name: SNW domain containing 1

Alternative Symbols: Bx42, SKIP, FUN20, Prp45, SKIIP, SKIP1, PRPF45, NCOA-62

Protein Name: SNW domain-containing protein 1

Molekulargewicht: 61kDa

Gen-ID: 22938

NCBI Accession: NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway