PPP1R12B Antikörper (AA 660-930)

Produktnummer ABIN7269677

Der Kaninchen Polyklonal Anti-PPP1R12B-Antikörper wurde für WB validiert. Er ist geeignet, PPP1R12B in Proben von Human zu detektieren.

Kurzübersicht für PPP1R12B Antikörper (AA 660-930) (ABIN7269677)

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R12B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPP1R12B Antikörper

Bindungsspezifität: AA 660-930

Verwendungszweck: PPP1R12B Rabbit pAb

Sequenz: TFSRSRAERQ AQEQPREKPT DTEGLEGSPE KHEPSAVPAT EAGEGQQPWG RSLDEEPICH RLRCPAQPDK PTTPASPSTS RPSLYTSSHL LWTNRFSVPD SESSETTTNT TTAKEMDKNE NEEADLDEQS SKRLSIRERR RPKERRRGTG INFWTKDEDE TDGSEEVKET WHERLSRLES GGSNPTTSDS YGDRASARAR REAREARLAT LTSRVEEDSN RDYKKLYESA LTENQKLKTK LQEAQLELAD IKSKLEKVAQ QKQEKTSDRS S

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPP1R12B

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Andere Bezeichnung: PPP1R12B

Hintergrund: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011],MYPT2,PP1bp55,PPP1R12B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Motor Proteins,PPP1R12B

Gen-ID: 4660

UniProt: O60237

Pathways: M Phase