PCSK9 Antikörper

Produktnummer ABIN7269570

Dieses Anti-PCSK9-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von PCSK9 in WB. Geeignet für Human.

Kurzübersicht für PCSK9 Antikörper (ABIN7269570)

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PCSK9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCSK9 Antikörper

Verwendungszweck: Proprotein Convertase 9(PCSK9) Rabbit mAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Proprotein Convertase 9(PCSK9)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Andere Bezeichnung: PCSK9

Hintergrund: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9,Amino acid metabolism,Apoptosis,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Neural Stem Cells,RNA Binding,Stem Cells,Ubiquitin,PCSK9

Molekulargewicht: 62,78kDa

Gen-ID: 255738

UniProt: Q8NBP7