PHKA1 Antikörper (AA 600-820)

Produktnummer ABIN7269367

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHKA1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PHKA1 Antikörper (AA 600-820) (ABIN7269367)

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHKA1 Antikörper

Bindungsspezifität: AA 600-820

Verwendungszweck: PHKA1 Rabbit pAb

Sequenz: QTGKLSEFLT TSCCTHLSFM DPGPEGKLYS EDYDDNYDYL ESGNWMNDYD STSHARCGDE VARYLDHLLA HTAPHPKLAP TSQKGGLDRF QAAVQTTCDL MSLVTKAKEL HVQNVHMYLP TKLFQASRPS FNLLDSPHPR QENQVPSVRV EIHLPRDQSG EVDFKALVLQ LKETSSLQEQ ADILYMLYTM KGPDWNTELY NERSATVREL LTELYGKVGE I

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human PHKA1 (NP_001116142.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHKA1

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Andere Bezeichnung: PHKA1

Hintergrund: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.,PHKA1,PHKA,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Calcium Signaling,PHKA1

Molekulargewicht: 129kDa/135kDa/137kDa

Gen-ID: 5255

UniProt: P46020

Pathways: Cellular Glucan Metabolic Process