PHKA1 Antikörper (C-Term)

Produktnummer ABIN2856675

Produktdetails anti-PHKA1 Antikörper

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Mouse (96 %), Rat (95 %)

Produktmerkmale: Rabbit Polyclonal antibody to PHKA1 (phosphorylase kinase, alpha 1 (muscle))
PHKA1 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human PHKA1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PHKA1

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Andere Bezeichnung: PHKA1 (PHKA1 Produkte)

Synonyme: PHKA1 antikoerper, wu:fl37h01 antikoerper, 5330411D17 antikoerper, 9830108K24Rik antikoerper, Phka antikoerper, Pcyt1b antikoerper, PHKA antikoerper, phosphorylase kinase regulatory subunit alpha 1 antikoerper, phosphorylase kinase, alpha 1a (muscle) antikoerper, phosphorylase kinase, alpha 1 (muscle) antikoerper, phosphorylase kinase alpha 1 antikoerper, PHKA1 antikoerper, phka1a antikoerper, phka1 antikoerper, Phka1 antikoerper

Hintergrund: The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 2.7.1.38), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB, MIM 172490), and gamma (PHKG1, MIM 172470 and PHKG2, MIM 172471) subunits have several isoforms, the delta subunit is calmodulin (CALM1, MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM]

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side

Molekulargewicht: 137 kDa

Gen-ID: 5255

Pathways: Cellular Glucan Metabolic Process