PDE1C Antikörper (AA 435-634)

Produktnummer ABIN7269300

Dieses Anti-PDE1C-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDE1C in WB. Geeignet für Human.

Kurzübersicht für PDE1C Antikörper (AA 435-634) (ABIN7269300)

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE1C Antikörper

Bindungsspezifität: AA 435-634

Verwendungszweck: PDE1C Rabbit pAb

Sequenz: VEPTFTVLTD MTEKIVSPLI DETSQTGGTG QRRSSLNSIS SSDAKRSGVK TSGSEGSAPI NNSVISVDYK SFKATWTEVV HINRERWRAK VPKEEKAKKE AEEKARLAAE EQQKEMEAKS QAEEGASGKA EKKTSGETKN QVNGTRANKS DNPRGKNSKA EKSSGEQQQN GDFKDGKNKT DKKDHSNIGN DSKKTDDSQE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 435-634 of human PDE1C (NP_001177985.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDE1C

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Andere Bezeichnung: PDE1C

Hintergrund: This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.,PDE1C,Hcam3,cam-PDE 1C,hCam-3,cam-PDE1C,Signal Transduction,PDE1C

Molekulargewicht: 72kDa/80kDa/86kDa

Gen-ID: 5137

UniProt: Q14123

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma