ORC2 Antikörper (AA 458-577)

Produktnummer ABIN7269109

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ORC2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ORC2 Antikörper (AA 458-577) (ABIN7269109)

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ORC2 Antikörper

Bindungsspezifität: AA 458-577

Verwendungszweck: ORC2 Rabbit pAb

Sequenz: TSYENSLLVK QSGSLPLSSL THVLRSLTPN ARGIFRLLIK YQLDNQDNPS YIGLSFQDFY QQCREAFLVN SDLTLRAQLT EFRDHKLIRT KKGTDGVEYL LIPVDNGTLT DFLEKEEEEA

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 458-577 of human ORC2 (NP_006181.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ORC2

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Andere Bezeichnung: ORC2

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.,ORC2,ORC2L,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,ORC2

Molekulargewicht: 65kDa

Gen-ID: 4999

UniProt: Q13416