Notch1 Antikörper

Produktnummer ABIN7268958

Dieses Anti-Notch1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Notch1 in WB und IP. Geeignet für Human.

Kurzübersicht für Notch1 Antikörper (ABIN7268958)

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Notch1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Notch1 Antikörper

Verwendungszweck: Notch1 Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Notch1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Notch1

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Andere Bezeichnung: NOTCH1

Hintergrund: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016],AOS5,AOVD1,TAN1,hN1,NOTCH1,Activated NOTCH1,notch 1,Cardiovascular,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Neural Stem Cell marker,Epigenetics & Nuclear Signaling,ESC Pluripotency and Differentiation,Heart,Heart_Cardiogenesis,Hematopoietic Progenitors,Neurodegenerative Diseases,Neuroscience,Notch Signaling Pathway,Signal Transduction,Stem Cells,Transcription Factors,NOTCH1

Molekulargewicht: 125kDa

Gen-ID: 4851

UniProt: P46531

Pathways: Notch Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development