NPHP1 Antikörper

Produktnummer ABIN7268847

This anti-NPHP1 antibody (ABIN7268847) is a Rabbit Monoclonal antibody detecting NPHP1 in WB. Suitable for Human.

Quick Overview for NPHP1 Antikörper (ABIN7268847)

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NPHP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NPHP1 Antikörper

Verwendungszweck: NPHP1 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NPHP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NPHP1

Target: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Andere Bezeichnung: NPHP1

Hintergrund: This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.,NPHP1,JBTS4,NPH1,SLSN1,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,NPHP1

Molekulargewicht: 69kDa/77kDa/83kDa

Gen-ID: 4867

UniProt: O15259