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MICA Antikörper

MICA Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7268508
  • Target Alle MICA Antikörper anzeigen
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Reaktivität
    • 69
    • 18
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    Human
    Wirt
    • 36
    • 33
    Kaninchen
    Klonalität
    • 37
    • 33
    Monoklonal
    Konjugat
    • 44
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MICA Antikörper ist unkonjugiert
    Applikation
    • 44
    • 37
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    MICA Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human MICA.
    Isotyp
    IgG
    Top Product
    Discover our top product MICA Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Andere Bezeichnung
    MICA (MICA Produkte)
    Synonyme
    MIC-A antikoerper, PERB11.1 antikoerper, MHC class I polypeptide-related sequence A antikoerper, MICA antikoerper
    Hintergrund
    This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.,MICA, MIC-A, PERB11.1, MHC class I polypeptide-related sequence A,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MICA
    Molekulargewicht
    42-70kDa
    Gen-ID
    100507436
    UniProt
    Q29983
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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