KDM2A Antikörper
Kurzübersicht für KDM2A Antikörper (ABIN7268326)
Target
Alle KDM2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- KDM2A Rabbit pAb
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human KDM2A.
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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Andere Bezeichnung
- KDM2A
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Hintergrund
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.,KDM2A, CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA, lysine demethylase 2A,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Demethylation,Epigenetics & Nuclear Signaling,KDM2A
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Molekulargewicht
- 69kDa/81kDa/89kDa/96kDa/132kDa
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Gen-ID
- 22992
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UniProt
- Q9Y2K7
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Pathways
- Warburg Effekt
Target
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