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Leptin Receptor Antikörper

Der Rabbit Monoclonal Anti-Leptin Receptor-Antikörper wurde für WB, IHC validiert. Er ist geeignet, Leptin Receptor in Proben von Human zu detektieren.
Produktnummer ABIN7268210

Kurzübersicht für Leptin Receptor Antikörper (ABIN7268210)

Target

Alle Leptin Receptor (LEPR) Antikörper anzeigen
Leptin Receptor (LEPR)

Reaktivität

  • 108
  • 75
  • 52
  • 20
  • 12
  • 3
  • 3
  • 1
Human

Wirt

  • 118
  • 16
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 113
  • 26
Monoklonal

Konjugat

  • 56
  • 11
  • 8
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser Leptin Receptor Antikörper ist unkonjugiert

Applikation

  • 89
  • 41
  • 37
  • 36
  • 31
  • 26
  • 16
  • 12
  • 9
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Verwendungszweck

    Leptin Receptor Rabbit mAb

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Monoclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    A synthesized peptide derived from human Leptin Receptor

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Leptin Receptor (LEPR)

    Andere Bezeichnung

    LEPR

    Hintergrund

    The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010],CD295,LEP-R,LEPRD,OB-R,OBR,LEPR,AMPK Signaling Pathway,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Growth factors,Immunology & Inflammation,Lipid Metabolism,Lipids,Lipids_Fatty Acids,Signal Transduction,LEPR

    Molekulargewicht

    96kDa/102kDa/103kDa/109kDa/132kDa

    Gen-ID

    3953

    UniProt

    P48357

    Pathways

    JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
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