LGMN Antikörper

Produktnummer ABIN7268208

Dieser Anti-LGMN Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von LGMN in WB. Geeignet für Human.

Kurzübersicht für LGMN Antikörper (ABIN7268208)

Target: LGMN (Legumain (LGMN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LGMN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LGMN Antikörper

Verwendungszweck: Legumain (LGMN) Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Legumain (LGMN) (LGMN)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LGMN

Target: LGMN (Legumain (LGMN))

Andere Bezeichnung: LGMN

Hintergrund: This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008],AEP, LGMN1, PRSC1,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_Bone,Immunology & Inflammation,Signal Transduction,Ubiquitin,LGMN

Molekulargewicht: 36,57kDa

Gen-ID: 5641

UniProt: Q99538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades