PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
KIF7
(Kinesin Family Member 7 (KIF7))
Andere Bezeichnung
KIF7
Hintergrund
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.,KIF7,ACLS,AGBK,HLS2,JBTS12,UNQ340,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Hedgehog Signaling Pathway,Stem Cells,KIF7