KIF5B Antikörper (AA 650-770)
Kurzübersicht für KIF5B Antikörper (AA 650-770) (ABIN7268136)
Target
Alle KIF5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 650-770
-
Verwendungszweck
- KIF5B Rabbit pAb
-
Sequenz
- LQNVEQKKRQ LEESVDALSE ELVQLRAQEK VHEMEKEHLN KVQTANEVKQ AVEQQIQSHR ETHQKQISSL RDEVEAKAKL ITDLQDQNQK MMLEQERLRV EHEKLKATDQ EKSRKLHELT V
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 650-770 of human KIF5B (NP_004512.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- KIF5B (Kinesin Family Member 5B (KIF5B))
-
Andere Bezeichnung
- KIF5B
-
Hintergrund
- Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs toward the immune synapse between effector NK lymphocytes and target cells.,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,KIF5B
-
Molekulargewicht
- 109kDa
-
Gen-ID
- 3799
-
UniProt
- P33176
-
Pathways
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
Target
-