KIF20B Antikörper (AA 1200-1500)

Produktnummer ABIN7268126

Der Kaninchen Polyklonal Anti-KIF20B-Antikörper wurde für WB und IF validiert. Er ist geeignet, KIF20B in Proben von Human zu detektieren.

Kurzübersicht für KIF20B Antikörper (AA 1200-1500) (ABIN7268126)

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF20B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-KIF20B Antikörper

Bindungsspezifität: AA 1200-1500

Verwendungszweck: KIF20B Rabbit pAb

Sequenz: KHLLQLKEEE EETNRQETEK LKEELSASSA RTQNLKADLQ RKEEDYADLK EKLTDAKKQI KQVQKEVSVM RDEDKLLRIK INELEKKKNQ CSQELDMKQR TIQQLKEQLN NQKVEEAIQQ YERACKDLNV KEKIIEDMRM TLEEQEQTQV EQDQVLEAKL EEVERLATEL EKWKEKCNDL ETKNNQRSNK EHENNTDVLG KLTNLQDELQ ESEQKYNADR KKWLEEKMML ITQAKEAENI RNKEMKKYAE DRERFFKQQN EMEILTAQLT EKDSDLQKWR EERDQLVAAL EIQLKALISS N

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIF20B

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Andere Bezeichnung: KIF20B

Hintergrund: Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.,KIF20B,CT90,KRMP1,MPHOSPH1,MPP-1,MPP1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Motor Proteins,KIF20B

Molekulargewicht: 59kDa/199kDa/206kDa/210kDa/214kDa

Gen-ID: 9585

UniProt: Q96Q89

Pathways: M Phase