IRS1 Antikörper (pSer612)
Kurzübersicht für IRS1 Antikörper (pSer612) (ABIN7267895)
Target
Alle IRS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer612
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Verwendungszweck
- Phospho-IRS1-S612 Rabbit pAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Phosphorylated Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding S612 of human IRS1
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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Andere Bezeichnung
- IRS1
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Hintergrund
- This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.,HIRS-1,IRS1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Protein phosphorylation,IRS1
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Molekulargewicht
- 131kDa
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Gen-ID
- 3667
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UniProt
- P35568
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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