INSIG1 Antikörper (C-Term)
Kurzübersicht für INSIG1 Antikörper (C-Term) (ABIN7267887)
Target
Alle INSIG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- INSIG1 Rabbit pAb
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Sequenz
- LWWTFDRSRS GLGLGITIAF LATLITQFLV YNGVYQYTSP DFLYIRSWLP CIFFSGGVTV GNIGRQLAMG VPEKPHSD
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human INSIG1 (NP_005533.2).
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Isotyp
- IgG
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anti-Insulin Induced Gene 1 (INSIG1) (AA 1-87) antibody
INSIG1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibodyINSIG1 Reaktivität: Human, Maus WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Kaninchen, Hund, Meerschweinchen, Schwein, Affe, Hamster, Xenopus laevis, Fledermaus, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Kaninchen, Hund, Meerschweinchen, Schaf, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Kaninchen, Schaf, Schwein, Hamster, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reaktivität: Human, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Kaninchen, Hund, Meerschweinchen, Schaf, Schwein, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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Andere Bezeichnung
- INSIG1
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Hintergrund
- This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism, lipogenesis, and glucose homeostasis. The encoded protein has six transmembrane helices which contain an effector protein binding site. It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), and is essential for the sterol-mediated trafficking of these two proteins. It promotes the endoplasmic reticulum retention of SCAP and the ubiquitin-mediated degradation of HMG-CoA reductase. Alternative splicing results in multiple transcript variants.,INSIG1,CL6,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,INSIG1
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Molekulargewicht
- 17kDa/29kDa
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Gen-ID
- 3638
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UniProt
- O15503
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Pathways
- ER-Nucleus Signaling
Target
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