HTRA3 Antikörper (AA 334-453)
Kurzübersicht für HTRA3 Antikörper (AA 334-453) (ABIN7267790)
Target
Alle HTRA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 334-453
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Verwendungszweck
- HTRA3 Rabbit pAb
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Sequenz
- SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
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Andere Bezeichnung
- HTRA3
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Hintergrund
- Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.,HTRA3,Prsp,Tasp,Signal Transduction,Neuroscience,Calcium Signaling,HTRA3
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Molekulargewicht
- 37kDa/48kDa
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Gen-ID
- 94031
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UniProt
- P83110
Target
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