HTRA3 Antikörper (AA 334-453)

Produktnummer ABIN7267790

Produktdetails anti-HTRA3 Antikörper

Target: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Bindungsspezifität: AA 334-453

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: HTRA3 Rabbit pAb

Sequenz: SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HTRA3

Target: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Andere Bezeichnung: HTRA3 (HTRA3 Produkte)

Synonyme: HTRA3 antikoerper, Prsp antikoerper, Tasp antikoerper, 2210021K23Rik antikoerper, 9530081K03Rik antikoerper, RGD1308120 antikoerper, Trypsin-like serine protease antikoerper, HtrA serine peptidase 3 antikoerper, htrA3 antikoerper, HTRA3 antikoerper, Htra3 antikoerper

Hintergrund: Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.,HTRA3,Prsp,Tasp,Signal Transduction,Neuroscience,Calcium Signaling,HTRA3

Molekulargewicht: 37kDa/48kDa

Gen-ID: 94031

UniProt: P83110