HDAC8 Antikörper

Produktnummer ABIN7267714

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch HDAC8 in WB, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HDAC8 Antikörper (ABIN7267714)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Güteklasse: KO Validated

Produktdetails anti-HDAC8 Antikörper

Verwendungszweck: [KO Validated] HDAC8 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human HDAC8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS,Cardiovascular,Epigenetics & Nuclear Signaling,Heart,Heart_Hypertrophy,Immunology & Inflammation,NF-kB Signaling Pathway,Nuclear Receptor Signaling,Stem Cells,HDAC8

Molekulargewicht: 42kDa

Gen-ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process