HCK Antikörper (AA 324-505)

Produktnummer ABIN7267612

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HCK in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HCK Antikörper (AA 324-505) (ABIN7267612)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HCK Antikörper

Bindungsspezifität: AA 324-505

Verwendungszweck: HCK Rabbit pAb

Sequenz: LKSDEGSKQP LPKLIDFSAQ IAEGMAFIEQ RNYIHRDLRA ANILVSASLV CKIADFGLAR VIEDNEYTAR EGAKFPIKWT APEAINFGSF TIKSDVWSFG ILLMEIVTYG RIPYPGMSNP EVIRALERGY RMPRPENCPE ELYNIMMRCW KNRPEERPTF EYIQSVLDDF YTATESQYQQ QP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 324-505 of human HCK (NP_001165600.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Andere Bezeichnung: HCK

Hintergrund: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.,HCK,JTK9,p59Hck,p61Hck,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,Immunology & Inflammation,HCK

Molekulargewicht: 57kDa/59kDa

Gen-ID: 3055

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling