GLI3 Antikörper (AA 800-900)

Produktnummer ABIN7267386

Der Kaninchen Polyklonal anti-GLI3 Antikörper (ABIN7267386) detektiert spezifisch GLI3 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GLI3 Antikörper (AA 800-900) (ABIN7267386)

Target: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GLI3 Antikörper

Bindungsspezifität: AA 800-900

Verwendungszweck: GLI3 Rabbit pAb

Sequenz: KAPAVSPLIG NGTQSNNTCS LGGPMTLLPG RSDLSGVDVT MLNMLNRRDS SASTISSAYL SSRRSSGISP CFSSRRSSEA SQAEGRPQNV SVADSYDPIS T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800-900 of human GLI3 (NP_000159.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GLI3

Target: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Andere Bezeichnung: GLI3

Hintergrund: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.,GLI3,ACLS,GCPS,GLI3-190,GLI3FL,PAP-A,PAPA,PAPA1,PAPB,PHS,PPDIV,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI3

Molekulargewicht: 169kDa

Gen-ID: 2737

UniProt: P10071

Pathways: Hedgehog Signalweg