GSPT1 Antikörper (AA 138-420)
Kurzübersicht für GSPT1 Antikörper (AA 138-420) (ABIN7267321)
Target
Alle GSPT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 138-420
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Verwendungszweck
- GSPT1 Rabbit pAb
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Sequenz
- SMELSEPIEN GETEMSPEES WEHKEEISEA EPGGGSLGDG RPPEESAHEM MEEEEEIPKP KSVVAPPGAP KKEHVNVVFI GHVDAGKSTI GGQIMYLTGM VDKRTLEKYE REAKEKNRET WYLSWALDTN QEERDKGKTV EVGRAYFETE KKHFTILDAP GHKSFVPNMI GGASQADLAV LVISARKGEF ETGFEKGGQT REHAMLAKTA GVKHLIVLIN KMDDPTVNWS NERYEECKEK LVPFLKKVGF NPKKDIHFMP CSGLTGANLK EQSDFCPWYI GLP
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 138-420 of human GSPT1 (NP_001123478.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GSPT1 (G1 To S Phase Transition 1 (GSPT1))
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Andere Bezeichnung
- GSPT1
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Hintergrund
- Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity. Stimulates the activity of ETF1 (By similarity. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF of mRNA from viruses and cellular genes.,GSPT1,551G9.2,ETF3A,GST1,eRF3a,Epigenetics & Nuclear Signaling,RNA Binding,GSPT1
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Molekulargewicht
- 55kDa/68kDa
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Gen-ID
- 2935
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UniProt
- P15170
Target
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