FIG4 Antikörper (AA 608-907)

Produktnummer ABIN7267203

Dieser Anti-FIG4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FIG4 in WB. Geeignet für Human.

Kurzübersicht für FIG4 Antikörper (AA 608-907) (ABIN7267203)

Target: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FIG4 Antikörper

Bindungsspezifität: AA 608-907

Verwendungszweck: FIG4 Rabbit pAb

Sequenz: WELPTDFYLH HKNTMRLLPT RRSYTYWWTP EVIKHLPLPY DEVICAVNLK KLIVKKFHKY EEEIDIHNEF FRPYELSSFD DTFCLAMTSS ARDFMPKTVG IDPSPFTVRK PDETGKSVLG NKSNREEAVL QRKTAASAPP PPSEEAVSSS SEDDSGTDRE EEGSVSQRST PVKMTDAGDS AKVTENVVQP MKELYGINLS DGLSEEDFSI YSRFVQLGQS QHKQDKNSQQ PCSRCSDGVI KLTPISAFSQ DNIYEVQPPR VDRKSTEIFQ AHIQASQGIM QPLGKEDSSM YREYIRNRYL

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 608-907 of human FIG4 (NP_055660.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FIG4

Target: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Andere Bezeichnung: FIG4

Hintergrund: The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.,FIG4,ALS11,BTOP,CMT4J,KIAA0274,SAC3,YVS,dJ249I4.1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,FIG4

Molekulargewicht: 103kDa

Gen-ID: 9896

UniProt: Q92562

Pathways: Inositol Metabolic Process