EDARADD Antikörper (AA 1-215)

Produktnummer ABIN7266900

Dieses Anti-EDARADD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EDARADD in WB. Geeignet für Human.

Kurzübersicht für EDARADD Antikörper (AA 1-215) (ABIN7266900)

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDARADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EDARADD Antikörper

Bindungsspezifität: AA 1-215

Verwendungszweck: EDARADD Rabbit pAb

Sequenz: MGLRTTKQMG RGTKAPGHQE DHMVKEPVED TDPSTLSFNM SDKYPIQDTE LPKAEECDTI TLNCPRNSDM KNQGEENGFP DSTGDPLPEI SKDNSCKENC TCSSCLLRAP TISDLLNDQD LLDVIRIKLD PCHPTVKNWR NFASKWGMSY DELCFLEQRP QSPTLEFLLR NSQRTVGQLM ELCRLYHRAD VEKVLRRWVD EEWPKRERGD PSRHF

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EDARADD

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Andere Bezeichnung: EDARADD

Hintergrund: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,EDARADD,ECTD11A,ECTD11B,ED3,EDA3,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,EDARADD

Molekulargewicht: 23kDa/24kDa

Gen-ID: 128178

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway