DRAP1 Antikörper (AA 50-150)

Produktnummer ABIN7266844

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DRAP1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DRAP1 Antikörper (AA 50-150) (ABIN7266844)

Target: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DRAP1 Antikörper

Bindungsspezifität: AA 50-150

Verwendungszweck: DRAP1 Rabbit pAb

Sequenz: LKKACQVTQS RNAKTMTTSH LKQCIELEQQ FDFLKDLVAS VPDMQGDGED NHMDGDKGAR RGRKPGSGGR KNGGMGTKSK DKKLSGTDSE QEDESEDTDT D

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human DRAP1 (NP_006433.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DRAP1

Target: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Andere Bezeichnung: DRAP1

Hintergrund: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008],NC2-alpha,DRAP1,Epigenetics & Nuclear Signaling,Transcription Factors,DRAP1

Gen-ID: 10589

UniProt: Q14919