DNASE1 Antikörper (AA 30-235)

Produktnummer ABIN7266733

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DNASE1 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DNASE1 Antikörper (AA 30-235) (ABIN7266733)

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-DNASE1 Antikörper

Bindungsspezifität: AA 30-235

Verwendungszweck: DNASE1 Rabbit pAb

Sequenz: IQTFGETKMS NATLVSYIVQ ILSRYDIALV QEVRDSHLTA VGKLLDNLNQ DAPDTYHYVV SEPLGRNSYK ERYLFVYRPD QVSAVDSYYY DDGCEPCGND TFNREPAIVR FFSRFTEVRE FAIVPLHAAP GDAVAEIDAL YDVYLDVQEK WGLEDVMLMG DFNAGCSYVR PSQWSSIRLW TSPTFQWLIP DSADTTATPT HCAYDR

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human DNASE1 (NP_005214.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNASE1

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Andere Bezeichnung: DNASE1

Hintergrund: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,DNASE1,DNL1,DRNI,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DNASE1

Molekulargewicht: 19kDa/31kDa

Gen-ID: 1773

UniProt: P24855