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DNASE1 Antikörper

DNASE1 Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856669
  • Target Alle DNASE1 Antikörper anzeigen
    DNASE1 (Deoxyribonuclease I (DNASE1))
    Reaktivität
    • 59
    • 26
    • 14
    • 12
    Human
    Wirt
    • 56
    • 12
    • 1
    Kaninchen
    Klonalität
    • 59
    • 10
    Polyklonal
    Konjugat
    • 32
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNASE1 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 21
    • 16
    • 13
    • 13
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Affe
    Produktmerkmale
    Rabbit Polyclonal antibody to DNase I (deoxyribonuclease I)
    DNase I antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein corresponding to human DNase I.
    Isotyp
    IgG
    Top Product
    Discover our top product DNASE1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.19 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DNASE1 (Deoxyribonuclease I (DNASE1))
    Andere Bezeichnung
    deoxyribonuclease 1 (DNASE1 Produkte)
    Synonyme
    LOC397802 antikoerper, DNL1 antikoerper, DRNI antikoerper, AI788650 antikoerper, DNaseI antikoerper, Dnl1 antikoerper, dnase1-A antikoerper, zgc:92440 antikoerper, DNase I antikoerper, deoxyribonuclease 1 antikoerper, deoxyribonuclease I antikoerper, deoxyribonuclease I L homeolog antikoerper, Deoxyribonuclease I antikoerper, endA antikoerper, LOC397802 antikoerper, DNASE1 antikoerper, Dnase1 antikoerper, dnase1.L antikoerper, dnase1 antikoerper, CpipJ_CPIJ011184 antikoerper, CpipJ_CPIJ011185 antikoerper, CpipJ_CPIJ011186 antikoerper, CpipJ_CPIJ011187 antikoerper, CpipJ_CPIJ011190 antikoerper, CpipJ_CPIJ017803 antikoerper, Desal_1409 antikoerper, MPET_RS05255 antikoerper, METEV_RS02275 antikoerper, Plabr_0631 antikoerper
    Hintergrund
    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Cellular Localization: Secreted , Nucleus envelope
    Molekulargewicht
    31 kDa
    Gen-ID
    1773
    UniProt
    P24855
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