Cortactin Antikörper
Kurzübersicht für Cortactin Antikörper (ABIN7266511)
Target
Alle Cortactin (CTTN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Cortactin Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Cortactin
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cortactin (CTTN)
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Andere Bezeichnung
- CTTN
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Hintergrund
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],EMS1,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microfilaments,Protein phosphorylation,Signal Transduction,CTTN
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Molekulargewicht
- 80kDa
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Gen-ID
- 2017
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UniProt
- Q14247
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Pathways
- MAPK Signalweg
Target
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