Cortactin Antikörper

Produktnummer ABIN7266511

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Cortactin in WB, IHC, IP und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cortactin Antikörper (ABIN7266511)

Target: Cortactin (CTTN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cortactin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-Cortactin Antikörper

Verwendungszweck: Cortactin Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Cortactin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: CTTN

Hintergrund: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],EMS1,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microfilaments,Protein phosphorylation,Signal Transduction,CTTN

Molekulargewicht: 80kDa

Gen-ID: 2017

UniProt: Q14247

Pathways: MAPK Signalweg