CXCR1 Antikörper (AA 250-350)

Produktnummer ABIN7266317

Der Kaninchen Polyklonal Anti-CXCR1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CXCR1 in Proben von Human zu detektieren.

Kurzübersicht für CXCR1 Antikörper (AA 250-350) (ABIN7266317)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CXCR1 Antikörper

Bindungsspezifität: AA 250-350

Verwendungszweck: CXCR1 Rabbit pAb

Sequenz: IFLLCWLPYN LVLLADTLMR TQVIQESCER RNNIGRALDA TEILGFLHSC LNPIIYAFIG QNFRHGFLKI LAMHGLVSKE FLARHRVTSY TSSSVNVSSN L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Andere Bezeichnung: CXCR1

Hintergrund: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.,CXCR1,C-C,C-C-CKR-1,CD128,CD181,CDw128a,CKR-1,CMKAR1,IL8R1,IL8RA,IL8RBA,Cancer,Tumor immunology,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,CXCR1

Molekulargewicht: 39kDa

Gen-ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process