CD70
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000,FC,1:100 - 1:800
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % thimerosal, pH 7.4.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C (regular) or -20°C (long term). Avoid freeze
Target
CD70
(CD70 Molecule (CD70))
Andere Bezeichnung
CD70
Hintergrund
CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.,CD70